Biocatalysis is a technology using enzymes or wholes as catalysts for chemical transformation process. Biocatalysis is widely used in the synthesis of pharmaceutical intermediates, due to the high process efficiency, excellent selectivity, mild reaction conditions, environmental friendliness, renewability and other properties.

PharmaBlock's has collected over 700 enzymes, including but not limited to Ketoreductase, Transaminase, Hydrolase, Ene reductase, Amino acid lyase etc., along with large mutant libraries. Over 100 of these enzymes have been used in kilo-scale projects and above. The team also has developed the fermentation platform, enzyme engineering and direct evolution platform and biocatalysis process development platform to meet diverse project requirements.

Leveraging on our expertise in biocatlysis, the team is offering the services and solutions:

• Biocatalytic route design and library screening
• Biocatalysis process development and optimization
• Enzyme engineering and directed evolution
• Development and application of immobilized enzyme
• Enzyme fermentation

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